Fine needle aspiration cytology is a simple, easy to perform, cost effective, and easily repeated procedure for the diagnosis of thyroid cancer. It is a challenge to differentiate between follicular adenoma and follicular carcinoma without histology. Materials and methods Study design This was a cross sectional study with both prospective and retrospective arms carried out from January to April Of the histologically confirmed neoplastic cases, were correctly identified as a neoplasm on FNAC and recommended for surgery. The introduction of the new simplified Bethesda system for reporting Thyroid cytopathology into six categories logically relates to the prognosis of thyroid diseases and increases the reproducibility of diagnosis. Indian journal of endocrinology and metabolism.

Social demographic characteristics of patients who underwent thyroidectomy at Mulago Hospital during the study period prospective arm. J Pak Med Assoc. Nevertheless no noteworthy association between size and duration of growth and the presence of malignancy was found. Dissertation submitted in partial fulfillment for the award of degree of master of medicine in surgery of Makerere University. Based on the cytology findings, patients can be followed in cases of benign diagnosis and subjected to surgery in cases of malignant diagnosis thereby decreasing the rate of unnecessary surgery.

It is recommended as the first line investigation for the diagnosis of solitary thyroid nodule.

Written informed consent was obtained from patients both for the surgery and for inclusion in the study. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were The main goal of evaluating these nodules is to identify nodules with malignant potential.

The use of a thyyroid of galectin-3 and thyroid peroxidase for the diagnosis and prognosis of thyroid cancer. However, no case of medullary or anaplastic carcinoma was diagnosed in our study Fig. Our study showed that solitary thyroid nodules were 11 times more common in females than males.


The median duration of symptoms was weeks IQR — For the retrospective arm, blinding of the histopathologist to the corresponding cytological diagnosis with FNAC may not have been observed.

All the FNAC data available for these patients were reviewed blind to histological outcomes.

Journal of Thyroid Research

All patients with clinically diagnosed solitary thyroid nodule who were clinically and biochemically euthyroid were included for study. It is now noted that for differentiated thyroid carcinoma DTCthere is a changing trend towards the frequent occurrence of PTC compared to FTC and this may be attributable to wide spread iodization programs The use of standardized categorical systems for FNAC reporting can make results easier to understand for clinicians and give clear indications for therapeutic action.

thesis on thyroid fnac

The proportion of patients with malignancy was O Box Kampala – Uganda. Sinna EA, Ezzat N. Benign or suspicious neoplastic lesions diagnosed by FNAC and their comparison with histopathological diagnosis.

The incidence of higher number of papillary carcinoma than follicular carcinoma thyorid correspondent with other excerpts in the literature. East and Central African Journal of Surgery.

thesis on thyroid fnac

Amongst these, the most frequent one was papillary carcinoma and it was followed by follicular adenoma. The minimum and maximum nodule size was two and cm three cms respectively. Application of immunohistochemistry to thyroid neoplasms.


The Accuracy of Manual Fine Needle Aspiration Cytology in the Evaluation of Thyroid Cancer

The accuracy rate was recorded as FNAC is cost-effective, minimally invasive and highly accurate for investigating patients with thyroid cancer. Adopting the above mentioned reporting system the inclusion criteria ffnac our study were, the cytopathology categories IV, V and VI.

The slide was then placed in a solution of paraffin solvent xylol or tolunol to remove the paraffin.

For the retrospective arm, enough information was extracted as much as possible from the cytology and histopathology reports. This article has been cited by other articles in PMC.

The diagnostic accuracy of Correlation between FNAC diagnosis and final histological diagnosis, intraoperative frozen section diagnoses without intraoperative cytology and final histological diagnoses, and intraoperative frozen section diagnoses associated with intraoperative cytology and final histological diagnoses were Funding This study received no external thyroix.

The sensitivity for diagnosing malignancy on Tyyroid was Sinna EA, Ezzat N. De Groot L, Hennemann G.

thesis on thyroid fnac

All patients were evaluated by thorough clinical examination followed by routine investigations including haemogram, renal function tests, liver function tests, chest X-ray, lateral neck X-ray, thyroid function tests and, FNAC. Of the histologically confirmed neoplastic cases, were correctly identified as a neoplasm on FNAC and recommended for surgery.